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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '397d481f228cfb55ea3888802c12c55064c627f20aa3fb45a14dedf7dd21efdc' 
  AND token = '8VtTrp2YgxkNW45bxu4psuW+XEE4m0Z00tYTO8Tgcac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}