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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fe2454b67af771d64ba180d37a0f68d788a2a75d01a7006832a1171bf7a9ea1' 
  AND token = 'fJc8Goha2IJRPDlMKgPZHLAWhMtgDw5spviQSHi4dL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}