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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd5b844da0320466600f7c482bee08d9ac660554b1d7153c4dff17fab45c2f86' 
  AND token = 'besCLvn4n4nJxdOLDuyzerWFr1nS/p5sfBAKdkKAjf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}