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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d2ec85505f5a1d7351580adbde1f9648facdec2d023993a8d556e1d4a3b21ea' 
  AND token = 'ht8pmrh4RUMue3r3J0N1Fg2+o0OsI84vVdbEbeQZmfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}