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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73131b8da1e00ba27bb7c3755a79fe3494d0d28b2042f6b21660c052232b16e9' 
  AND token = 'PuIEsMMlT/Ra4dt4EwDFC+A+Xj1ph6uPh4hBBbOF2VA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}