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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '818ce4d825c3deb0dd047a6f9056b1d588899154269f90cbae1d5407bdbddc00' 
  AND token = 'dlfCKn6k7IqyuYiY5pzJl8p8fbze66EYcWa8m8oglZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}