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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d38783c47077a28531788ddff19313d997f8e41b8d262c3ff1ebd1a6b22cb1e' 
  AND token = 'uVtuuneZHHkEFTJ7lvlF2SPB5OAA6WwaHIC20OyKgck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}