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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1f366ebf7cca15b6ce86f5c69dc6110dc3cff1d3562bf0ce3401a03a407f0a2' 
  AND token = 'r7DGHTs3pYS+GwKaki85C9HGwOoAJ9svcNOxOAEm2lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}