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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a985b9795ffff1cc017dcfa0010365cfa07eefb407dc976c12e282b26153fe2' 
  AND token = 'R2zKz+AsSCGnoAnJEGl4OpIRvDQzSyxWpx30XW0OmDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}