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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ef94a49f749a54a71a529d2e8bc40698103b75e2e09e7d3360220556f16b154' 
  AND token = 'lctTZ+W0jWxd1zEN9TjAFnCrOzp5VChN3Dc5GaJpVqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}