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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '286ecea6d9932b6c01deff37a25d25dc426c65364e7031b0bfae4cca2c78ccb3' 
  AND token = '64l/5/C5QLfud5S5zoErFNv8iG6DeexToW860DdP870=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}