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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be197da9967661a5cf9c420c6a898273e58aab2d0d18ea57e09c6273cc0c6483' 
  AND token = 'IaC4NNL39Y60MJEnMttGGmJkpRzgtjAF1aAnfQe8hwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}