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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a80ce0893e44ec8aa9b23e4671b8ea4d8c5d7d1378cd983edc51f886aa56a47' 
  AND token = 'L21A5jxKju9KYKd6bZHgYGE+BMhpn5astAhD3YmEjBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}