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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '159705c14327a085da40434eed27693d0fa962e39086645e7c6870e117ab1272' 
  AND token = 'UnaP0FnGF2xiqxdoXryGc4H7OtDUXeX7Y6viKygBWVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}