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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1d42b9f02d515461df9f312c114ec07726893a6b7d7f19badbd641852cf596c' 
  AND token = 'nwM2cFoGikeGd4xg8hcl60fT8Q7DwfpNZwZW8Fu8nGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}