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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cfd3e936ed3320b1e989f197243ba003b355fbeb7bf60cace1da10993f68d9d' 
  AND token = 'loFtxwN/hQNqKI9QAbAOcCbJktfTl+eRMcJ15VHXpJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}