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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eb580dea635b4f37d0061e6cebfc79abed4019269c96f82cef50786d3baeab4' 
  AND token = '6EZELHg/QMu4ng6veFoB9Ftg6X+Pe3xZye+9r3H2ROs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}