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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6c0494e9fba9d6e7f659ad81abd081232001222af33fa249c2f54dedcee359c' 
  AND token = 'Ux8BylA3XHkClLnfWEvsAuDEt2SYAfYawRR80Bo9gUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}