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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0425e7ad69f52bde512860198516b30ab275edabcbbce4c5b3ac7e6944ce49f2' 
  AND token = 'yUEifN+733QhI8o3PtE6yCl/8gSXJ1nMErb58ogf6Lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}