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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3c7e2a18c3d67266dd31bb2c60218f66194bb9be90dd46c2ef47c54086097a8' 
  AND token = 'R0SQSF+cFX0pea/ZA06ZWqhlKot35X7maVFsrp1eKxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}