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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7de8ab42b045f9d77e9cd69a64c6352b3d4777610e3379cbb8fb157d1caf9044' 
  AND token = 'fNUSSrMyMsyQxKxGCId3/3g26HhNnatcsZEtU0/PM1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}