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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08e779391b71ca00bb47894dad69a7c1eb2a394e59998e17c003ab248c1b3a22' 
  AND token = 'k7M9FSVAya0uQLJ0u1Ajnqu8RsJhDD7Uns+zjR3eDY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}