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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b623862058509d69f1ee96b8e9fcddb06cb1ff25d93019f15d8fa2685f5c4368' 
  AND token = 'OFHh1ys7Z9epQARvwjOrh/tombh/Lk3fTEG8BVVWNUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}