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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e188ef2cfbbba4141acd1b01d0637574acba7f6203ff1d48ccb811677301a970' 
  AND token = 'Acz4EsimcB4Z33Q6zWbUbpZ1XGi5a5XdWuMfOJX2cYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}