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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '606db4120bab90a3476507304f526480fbfd6a19012c078bd1d6ed64914651e6' 
  AND token = 'q6M5Xb0Q9mkzheZS7LvZ/B8oVpuggNuGzI8JODSM45c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}