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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a61c07e4ba9c5f0a5c97d5a491386203830d45950e52e328a3b267b336cb1239' 
  AND token = 'mfkPhkg+t+4UyviP+56ArO5TrrKFwn3saiD83pW8cQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}