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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '311dfc5b11ff80ff255edf9986767742f8e5d4a8296f9550df751934a1adbf23' 
  AND token = 'iupFfAMMy8gLX7AMo33u9ZSk+UPBNaEAaDkZcqTmSR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}