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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d8d6d30b0897aa39653da65989d89f3aad7f1a8f32b0c00b48b2d0253daf25a' 
  AND token = 'D7WW77BSpxqAx5XxOD4M4oeFQgZAAMq0SJIveNpiWkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}