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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd31d00da9f362d97b58ca1a60d77750c2e6a9fc0079bd4e0653b1c512202d1c' 
  AND token = 'ecNxaIx0YSo0yg7+yMDmcM0KmEkGSes/sr8QzsNQPrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}