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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46404d96d112d024b1f07c477229e401dd1e53a238cc7392cf1a7bb8940abcd2' 
  AND token = 'WkDbn3d2rsxKH8QqeH9gf3IFl1Bd/w0nCJa+9CbsBnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}