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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b0624ca548ec9a6e1eb58c2cc1d66963f984993456f024aef54358f267a8778' 
  AND token = 'r2vDqwOPnurBWGacin9O8VcQOoafmM+pVz9X0faMUJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}