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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85439b2cc3cd7b5ab26d24661b02780716e486d12acf532a5e650f683a3cf740' 
  AND token = 'eo4he8mSaDik8Zwn3d+mYUvG4YCbi0PHubxy3+Mh3Bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}