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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e4af607a2a9b834ed77436be71117409b2e2386238aadd48ebbc53f0a8c88db' 
  AND token = 'YXoDQ5jbY1idC4B0FvgdPVdEa0/Z442eRceCFEJ8gEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}