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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b34ef1b3d70eedee05ea8d54a60f41194206186e01ec3cb1727aa594f67de2f' 
  AND token = 'F5T2TUuXJciiJg2rOsGDZeSP8sevYLe9bHAIYH0fXM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}