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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a66ecca28f0adaff740d0327b016fc186bf176be46ba2669631740c1a979aec4' 
  AND token = 'mMOVGQ1NtYBHPC5Y5G0vvgeS2q6Tzu7skvPQcDSL2MM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}