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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4780b06dd10b582d282f57d200829fc9fddf1d1a9b591af123bf1b710a49d25c' 
  AND token = '95oYNV5mpG98RaA/8sCItTzuYh3Zhswz8X360LsvqsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}