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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02b2e11f6daa11e881d4ab536b77a7f5527d8849c1ef6c8073425ea899a67d02' 
  AND token = 'XOZMZb9FMDoPWWaGBx8KsyobbgVbTYsoBUyhsYFNk5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}