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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f788220b1d23ffaf87eac6bf959b33c014e383160ecf5887edb1a8ada326f3' 
  AND token = 'ns3fmTSiMu3BVGP6uZfC/6z8P9fXpWNfMboxwRaI8Jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}