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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8f031fe09b76f35da79776ef4ed49072d4537c441c282c1670d9ad7d89de0f5' 
  AND token = '6het26yvqV5t7wIo8UhtMM5GvifUwBI2GTPGfqyeU08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}