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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bc85e790d647a3cc32db3f17938d20be3e9b07a7c295296e121c63fb5d1d5d5' 
  AND token = 'lWxfTnxzJrTNx9d0EVyltiMCUAYQ7YYHs9IBJ70PRHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}