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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac4d6c9a5bfcb3eaeaadebcf1d60c741a4d1a65935d7bee0debd088eda71129b' 
  AND token = 'KUxCmCfWEi97NMLdjoycjpTJsKjz3slaumrMG5901uQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}