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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2202b241e4e3096bdfdbd148b824b3b02ab6b31acc3ce298bbe284e95e4122d4' 
  AND token = 'R07q3mw1/uViJcYXL0jqihWDAFg3LR4HiCWs/zkaL9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}