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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a86958c5690c7979326d9b20de71f72bcc206edcfa55c2951d3921180330bcfe' 
  AND token = 'WWNE8DWHY43dNw88NS1dVypWpD+IA7Mk4YvABidRKgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}