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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b72ae3ad633aab7abe5d092382a02dbb917a8a6141e164a47d60ec98b069ea33' 
  AND token = '5KQrmMap4NqPex7Gj74gS8Gfh1/st1ujFC9PoA75bAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}