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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a3f5c21acaa28364dced54802e31aa6da6e87b9fb82f168b750c1ae8c136c8a' 
  AND token = '1bGsK1N+gOHGUQr1dcSpEAl0u8mq1+HXBeMG0JA5dJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}