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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c4be9d22dd51948634d86c2a114bf10d381603c8b2c1f7c2334a217e16342d5' 
  AND token = 'qAvYlWTRQ64eIJtsV3Ra5yAiH+O46SKuDVpyA+W/p0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}