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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40ab19b7221f2768302bc791e21b8cfd06e119164c39d3a72d1cf1d7eeb65ab6' 
  AND token = 'ExN5Z+VI1ilowrNBrj6EFdj9sO5dSx6/EShfPdjHHgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}