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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f417a5038b928f86cc19c4a797cfa3d02aa278b4df5eb09713c26d1d6ed16202' 
  AND token = 'IR5yal+d4BKmYCMgD6QCd/cWAHi8nZeZIcYOAqDpm9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}