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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c14d09f13dceaae2b4c4f4c560dacc2a069efb7438cedf1b3a36a3eaf4e4e90' 
  AND token = '7xmtXE9UqW7RcSR4YaLrzxJd4UNMiTM3ZhHI+VmBK7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}