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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '376f54390d3e45e855be7fc51057703bcb1705b0e7454aa358dcf5032c929cd0' 
  AND token = 'v/eIMSftt8baALYFEqA6WtXm/QZk/pfSlNTpK8iNB40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}